Located in the San Fernando Valley, 16907 San Fernando Mission Blvd. Granada Hills Ca, 818-363-8143
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CANINE PARVOVIRUS
& ITS PREVENTION WHAT IS IT? Canine
Parvovirus is a viral disease of dogs that was first reported in early 1978.
Parvovirus is capable of causing two different sets of clinical
problems. The first to be
recognized, and most common, is the “intestinal” form which is manifested
by diarrhea; often bloody vomiting, loss of appetite, depression, fever, and
sometimes death. The second
syndrome, the “cardiac” form, occurs in very young pups and is manifested
by an acute inflammation of the heart muscle. Any
age, breed or sex of dog could be affected by Parvovirus.
However, infection with Parvovirus does not automatically mean illness.
Several factors such as age, environment, stress, parasites and general
health status of each individual dog infected could affect the severity of
illness. The degree of illness
could range from very mild to unapparent to very severe, often resulting in
death. The disease is usually more
severe in young dogs (less than 6 months of age)
or old dogs. WHERE DID IT
COME FROM? Experts
agree that canine Parvovirus is closely related to Parvoviruses that affect
other animals. Where the virus
originally came from remains unknown, but it is possible that it is a mutant
from another Parvovirus that affects other species of animals.
Man is not known to be affected by canine Parvovirus.
Since its first appearance in 1978, canine Parvovirus has spread to
every continent in the world, probably the result of the hardy nature of the
virus. It is resistant to extremes
of temperature (i.e., it survives freezing and extreme heat) and is unharmed
by detergents, alcohols and common disinfectants.
Direct transmission occurs when an infected dog comes in contact with a
healthy dog. The virus is found in
heavy concentration in the infected dog’s stool.
The virus particles can be easily spread on shoes, clothing and other
inanimate objects. Fleas, as well
as people, can therefore act as indirect sources of infection.
Once it gets a foothold in a kennel, it is difficult to eliminate.
Oral Phase:
The disease process begins
with the oral ingestion of Parvovirus from the feces of an infected dog.
The virus initially invades the lymph glands of the throat (lymph nodes
and tonsils) where it multiplies. Following
multiplication in the lymph glands for l to 2 days, the virus then enters the
blood stream which causes the VIREMIA phase (virus in the blood). Viremia Phase:
This phase is characterized
by massive amounts of virus in the dog’s bloodstream, which in turn is
spread to all parts of the body, such as, the intestine, bone marrow, spleen,
other lymph nodes and the heart (in young pups less than 8 weeks of age).
As infection spreads, the symptoms of illness become apparent.
(See “symptoms” in next section).
The Viremia phase can last for approximately l to 9 days. Contagious Stage: The final phase in the cycle is the contagious or “shedding” phase. As many as 30 billion Parvovirus particles can be shed from the intestines of an infected dog in every ounce of stool. The highest concentration of virus in the stool is seen when the infected dog is showing signs of illness. A dog can, however, be a source of infection to other dogs without having observable signs of illness. Transmission can occur for at least 3 weeks after a dog becomes infected with the virus. Chronic “carriers” are not know to exist as in other virus disease. Parvovirus in the environment can infect susceptible dogs for many months once shed in the stool. What are the
symptoms?
The symptoms below indicate a problem
warranting medical attention. Early,
vigorous treatment of illness caused by canine Parvovirus infection is
imperative since vomiting and diarrhea can lead to dehydration and chemical
imbalance in the body. If your dog
shows these signs, see your veterinarian. Early
treatment can save lives. Cardiac Form
(less than 8 weeks of age) Sudden
death Crying,
difficulty breathing, gasping for breath Extreme
depression Weakness Unwillingness
to nurse Irregular
heartbeat Intestinal Form
(any age dog affected, but more severe in puppies). Depression Loss
of appetite Fever
(above 103 degrees F) Vomiting Diarrhea
with or without blood (more serious if blood present) Low
white blood count How is it
controlled?
Control of Parvovirus by sanitation
measures alone is extremely difficult because the virus is such a resistant,
hardy organism and because it is so easily spread.
Contact with other dogs and especially their stool, should be minimized.
Clorox diluted one part to 30 parts with water has been effective in
disinfecting inanimate objects such as clothing, floors, kennels, etc.
However, it is impractical, if not impossible, to disinfect public
streets, parks, etc. Isolation of
infected dogs is another method of control, although moderately effective.
Both of these measures will help reduce the amount of contagious virus in
the environment, but only vaccination will control the actual source of
infection, the contagious shedding dog. Vaccination
is the most effective control measure
for canine Parvovirus disease. A
properly immunized dog will have circulating antibodies in the blood that will
destroy Parvovirus following exposure. THE ROLE OF MATERNAL ANTIBODY IN PUPPY IMMUNIZATIONMaternal
antibodies are antibodies against Parvovirus which are passed from the mother to
the puppies through the “first milk” or colostrum.
They provide the puppy with an immediate temporary or “passive”
immunity. The mother obtains these
antibodies from prior vaccination or by natural exposure to Parvovirus.
However, maternal antibody is a two-edged sword; it protects the puppy
against disease early in life, but it also blocks active immunization.
In the case of Parvovirus, maternal antibody can interfere with
vaccination for as long as 14 to 16 weeks of age in some pups.
A refractory period can exist in some pups where very low, almost
undetectable levels of maternal antibody will inhibit the vaccination process
but will not prevent Parvovirus infection. Since
the level of maternal antibody varies from puppy to puppy, it
is important to begin vaccination at an early age and repeat every 2-3 weeks
until the puppy is at least 16 - 18 weeks old.
16907 San Fernando Mission Blvd. Granada Hills, Ca. 91344 818-363-8143
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